1 = poop, 2 = penny, 3 = bomb, 4 = key, 5 = red heart, 6 = pill, 7 = card, 8 = soul heart, 9 = gold heart, 10 = gold key, 11 = gold bomb, At the full 12 charges, a completely random effect will happen. Spindown Dice is the only dice item that cannot be copied by the D Infinity. Dead Bird) then Box of Friends will cause it to spawn but won't create duplicates, This can be used multiple times in the same room to generate more familiars, meaning you can get a level 4 meatboy or bandage girl by using this item 3 times in the same room, If used when you have no familiars, it will give you a Demon Baby temporarily, UNLOCK: Unlock this item by beating Greed Mode with Lilith, Isaac wears a dunce hat and fires 2 tears at once diagonally, similar to the R U A WIZARD pill tear pattern, * Item Room, Greed Mode Item Room, dunce cap, white, hat, cone, Replaces Isaac's tears with nails, which have increased knockback, The increased knockback will also affect Brimstone, which usually has no knockback at all, Gives you a familiar demon incubus that follows you and shoots tears that scale with your own tears in terms of damage, stats and also effects, It will mimic any tear effects you currently have and also copy your current stats, meaning it will fire with the same damage, fire rate and range, Incubus' damage is reduced by 25% when playing as characters other than Lilith, UNLOCK: Unlock this item by beating Blue Womb (Hush) with Lilith, Item Pool: Devil Room, Greed Mode Devil Room, A familiar blue head that will follow Isaac and fire tears copying his tear damage and effects, This familiar is very similar to Incubus, however it only copies damage and is not affected by tears or range upgrades, UNLOCK: Unlock this item by beating Blue Womb (Hush) with ??? These can be smaller or big batteries, Upon use, Mom's Bracelet allows you to grab objects in the room and throw them, damaging any enemies which are hit for 40 damage, Most objects can be thrown including pots, rocks, poops, tnt etc, Pressing the activate button again will drop the object where you stand, which doesn't consume a charge of use, Allows you to remove the skull on top of Host enemies, turning them into the red version, *, arm, moms, ring, bracers, zelda, gold band, golden band, power bracelet, When used, this item spawns a Peeper familiar for the current room, which deals 12 contact damage per tick to enemies and leaves red creep in its path, Using this item removes Isaac's right eye, causing tears from this eye to deal x1.5 your normal tear damage, Using it more than once in the same room will spawn multiple Peeper familiars, Fired tears now have a chance to summon a rift when they land on the ground, The spawned rift sucks in enemies, projectiles and pickups and deals damage to enemies caught inside for 2 seconds, The chance to fire the rift tear can improve based on your luck stat. Will take red hearts first before any other, Eve starts with this item after donating 439 coins to the Greed Donation Machine, UNLOCK: Unlock this item by beating Satan with Eve, Item Pool: Item Room, Curse Room, Demon Beggar, * devil pool, devil room pool, devil deal, the lost item pool, starting, silver, grey, gray, Upon use, this item refreshes the current floor with brand new rooms, monsters and items, as if you had entered a new floor, UNLOCK: Unlock this item by beating Satan with Blue Baby, Item Pool: Item Room, Secret Room, Devil Room, Demon Beggar, * secret room pool, item room, treasure room, item room pool, pill, tablet, drug, white, Holding the fire button charges a spin attack (Damage * 8 + 10). You avoid taking damage once every room. By selecting the button above, you can download The Binding of Isaac's APK. orange, moms wig, Gives a chance to heal 1/2 a red heart every time the in-game timer hits a new minute, There are no restrictions on when the regeneration effect happens as long as the game is not paused, so you can simply afk and heal over time, It's possible to find this item by blowing up Polyps (the weird red rocks found in the Womb floors), * boss room pool, boss room item, the lost item pool, purple, red, lump, When you get hit, you will sometimes cause hearts to drop on the floor, The chance to drop hearts is affected by your luck stat and at +29 Luck it will activate 50% of the time, * boss room pool, boss room item, the lost item pool, plasters, white, Everytime a bomb explodes, it will release a circle of 10 tears outwards, much like the Tammy's Head effect, The tears from each bomb deal a flat 25 damage and are affected by any tear modifiers Isaac has, The tears caused by Sad Bombs are much larger and do a lot more damage than Isaac's normal tears, * boss rush pool, boss rush room, item room, treasure room, item room pool, crying, face, Isaac's tears now bounce off walls and objects in the environment, such as rocks and pots, Allows tears to hit the same enemy multiple times, If you also have Lost Contact, tears will bounce off enemy projectiles instead of being destroyed, UNLOCK: Unlock this item by beating Mom's heart 2 times, Item Pool: Item Room, Greed Mode Item Room, * item room, treasure room, item room pool, orange, brown, bottle, jar, As you hold down the fire button, shots will float in the same place until you release the fire key again, Allows you to store up a lot of tears in the air and release them all at once, When the tears are released, they will fire off in the direction that Isaac was originally facing when it was created, * anti gravity, item room, treasure room, item room pool, anti gravity, atom, nucleus, All explosions now heal Isaac for 0.5 red hearts instead of hurting him, REPENTANCE - Pyromaniac now grants Isaac immunity to fire, but no longer protects against stomps or shockwaves. * item room, treasure room, item room pool, robo baby, robot baby, white, grey, gray, silver, red, A familiar which follows Isaac and drops half a red heart every 3 rooms, UNLOCK: Unlock this item by beating the Caves 30 times and defeating C.H.A.D, * lil chad, little chad, item room, treasure room, item room pool, the lost item pool, red, smile, face, bug, Any pickups are possible from this item, including Bombs, hearts, keys, coins, pills, batteries, tarot cards, runes etc, Doesn't produce microbatteries, only regular sized ones and rarely golden/mega batteries, UNLOCK: Unlock this item by beating each of the Seven Sins once, Item Pool: Item Room, Library, Devil Room, * library pool, library room, book room pool, devil pool, devil room pool, devil deal, item room, treasure room, item room pool, red 7 book, grey, gray, black, A blue cross that follows Isaac and drops a soul heart every 7-8 rooms, REPENTANCE - The Relic now generates soul hearts less frequently, UNLOCK: Unlock this item by beating the Isaac boss with Maggy, * angel room pool, god room pool, angel room item, item room, treasure room, item room pool, Beyond the womb floor, replaces all coin and key spawns with a random pickup as follows: Bomb - 26.6% chance. Broken hearts permanently subtract from your total possible health containers, UNLOCK: Unlock this card by defeating Ultra Greedier mode as Tainted Magdalene, Isaac turns to stone and can't move for 10 seconds, but your tear rate goes up significantly for the duration, UNLOCK: Unlock this card by defeating challenge #42 (Hot Potato), UNLOCK: Unlock this card by defeating challenge #43 (Cantripped), "May you see the value of all things in life", When used, all items and pickups in the current room are turned into money. - The Binding Of Isaac: Repentance #50; DOUBLE DEATH (CERTIFICATE)! Bethany - Activating an item using soul charges is sometimes free, Jacob & Esau - The character who picks up Birthright gains copies of three of the other character's passive items, UNLOCK: Unlock this item by defeating ??? Any Tarot card or rune on the floor or current held when picking this item up will change into a pill, Dice Shard counts as a card and will be converted, UNLOCK: Unlock this item by picking up 2 of the following items: Roid Rage, The Virus, Growth Hormones, Experimental Treatment or Speed Ball, * shop room pool, shop item pool, brown, purple, * boss room pool, boss room item, red, wedge, purple, triangle, The above stats only apply to tears fired from Isaac's left eye or with a 50% chance if you have an item which causes you to fire from a single source only, * boss room pool, boss room item, red, blob, circle, spot, * boss room pool, boss room item, grey, gray, Enemies touching placed bombs take 16 damage, Gives all bombs a burning effect when they explode, leaving fire on the floor which deals 22 damage to enemies, REPENTANCE - Hot Bombs now have greatly increased contact damage (increased from 1 to 16), and passively grants Isaac immunity to fire, * item room, treasure room, item room pool, fire, orange, flame, face, Isaac's tears now set enemies on fire, leaving a damage over time effect that does 4 or 6 damage per tick, There is a chance that tears that hit enemies will explode, leaving a small fire on the floor that damages enemies, Exploding tears deal damage * 2 + 22 per tick, The chance for tears to explode is affected by your luck stat and at +13 Luck it will activate every time, * item room, treasure room, item room pool, fire, flame, orange, back, ball, burning, When picked up, and at the start of each floor this rerolls all your current items, giving you a new item to replace each of the ones you had, Also rerolls all your stats at the same time, giving a random flat modifier that changes each time, Doesn't affect important items such as Polaroid, Negative and Key Pieces, UNLOCK: Unlock this item by beating Boss Rush with Lazarus, * secret room pool, mondrian, painting, yellow, blue, red, white, Tears now have a chance to apply the fear effect to enemies, which causes them to run away from Isaac, The chance to fear enemies is affected by your luck stat and at +20 Luck it will activate every time, An item only found in the devil room pool (Note: The Fallen boss pulls items from the Devil Room Pool), * devil pool, devil room pool, devil deal, grey, gray, fist, glow, Immunity to all floor curses (e.g. the lost item pool, grey, gray, A familiar which follows Isaac and shoots spectral tears that deal 3.5 damage, Ghost Baby fires tears at a rate of 1 tear per second, Can drop while destroying skulls in the Depths and Necropolis floors, * devil pool, devil room pool, devil deal, item room, treasure room, item room pool, white, spoopy, A spacebar item which allows Isaac to fire a blue flame that damages anything in its path for 23 damage per tick, Can cause up to a total of 276 potential damage, The flame destroys enemy shots, making it useful for bullet hell bosses, UNLOCK: Unlock this item by donating 900 coins to the Shop, * shop room pool, shop item pool, blue candle, grey, gray, silver, lamp, lantern, * boss room pool, boss room item, grey, gray, whip, cat o nine tails catonine tails, Upon use, re-rolls all pickup consumables in the current room into another random kind of pickup, This includes all types of pickup such as hearts, bombs, keys, coins, pills, tarot cards, chests, trinkets etc, UNLOCK: Unlock this item by beating the Chest with Isaac, * item room, treasure room, item room pool, dice pip, red, A familiar which follows Isaac and shoots two normal tears at once in a V-shaped pattern, Each of Harlequin Baby's tears deal 4 damage, Harlequin Baby fires tears at a rate of 1 tear per second, * item room, treasure room, item room pool, bug, eyes, pink, red, Tears now become missiles which deal huge damage to anything nearby, This item places a controllable red target on the ground which will cause a missile to fall from the sky and hit it after a short period of time, UNLOCK: Unlock this item by beating Challenge #19 (The Family Man), Item Pool: Secret Room Item Room (very low weight), * item room, treasure room, item room pool, fetus in a jar, bug, white, hat, pink, If a tear kills an enemy, it continues to travel forward with the leftover damage, * item room, treasure room, item room pool, large eye, cyclops, one eye, blue, white, A shadow follows Isaac and stomps on enemies randomly, dealing 40 damage per stomp (2 damage ticks at 20 damage each). Score Definitions. ), UNLOCK: Unlock this trinket by defeating Mother as Tainted Isaac, Causes Item rooms and Shops to appear in the Cathedral, UNLOCK: Unlock this trinket by defeating Isaac, ?? changes: Brimstone to brimstone gfuel isaac's tears to isaac . - When used will consume your current trinket, destroying it and giving you its effect permanently. Join. You can release the enemy early by using it again, Tainted Jacob starts with this item. Effect persists between rooms while the time period is active, Speed Down - Reduces your speed stat by -0.12, Speed Up - Increases your speed stat by +0.15, Tears Down - Reduces your tears stat by -0.28, Tears Up - Increases your tears stat by 0.35, Telepills - Teleports you to a random room when used. Gives a small chance when entering a room for enemies to be petrified for 4 seconds. Smaller enemies spawn 2-3 tears, and bosses spawn a maximum of 16, Tears from this effect maintain tear modifiers and status effects that Isaac currently has, Isaac doesn't take damage from the tears created by this item, Every time you take damage, a tiny Isaac familiar will spawn, which follows you and shoots tears at nearby enemies that deal 1.3 Damage, The mini-Isaacs stay with you between floors, but can die if they take too much damage, Maximum number of mini-Isaacs is 16 at one time, Mini-Isaac's keep some of the abilities and appearance that Isaac has - e.g. Items - The Official Binding of Isaac: IPECAC Wiki Items Edit Items are an integral part of game-play in The Binding of Isaac: Rebirth. A familiar that follows Isaac and charges forwards very slowly, dealing 2.7 damage per tick to any enemies it comes into contact with, Almost identical to the Little Chubby familiar, but this one moves much more slowly and deals less damage, REPENTANCE - The damage tick rate on Big Chubby has been increased, Upon use, this item deals 9,999,999 damage to all enemies in the room and then kills you 3 seconds later, This is a single use active item, meaning it is destroyed after using it, Does not kill both phases of multi-phase bosses like Hush or Ultra Greed, If used to kill a boss, the kill still counts as a victory for post-it note completion marks, but the run will still get a game over, Delirium's death animation takes longer than 3 seconds, meaning you will die before it can count as a completion mark. The first piece drops by beating the first floor boss within 1 minute then bombing the shadow in the first room. UNLOCK: Unlock this item by defeating The Beast as ??? Each use also gives +0.5 Black Hearts, however this is stays between rooms unlike the other effects, Allows Isaac to deal 40 contact damage to enemies for the current room. ?, Satan and The Lamb as Tainted Lilith, All shops only sell familiars while holding this trinket, If you enter a shop while holding this trinket, the effect won't undo by dropping it until you move to a new floor, UNLOCK: Unlock this trinket by defeating Mother as Tainted Lilith, Every time an enemy dies you have a chance to gain a random Locust, Different color Locusts correspond to the horsemen. Secret Rooms, UNLOCK: Unlock this trinket by defeating Mother as Tainted Lazarus, Every time you take damage, you drop up to 2 different types of consumables on the ground, Dropped consumables can be any variant of its kind - e.g. The Binding of Isaac: Rebirth. After taking two hits, the fire will be extinguished, The Book can be held at the same time as another active item. lightning, bolt, hot garbage, Tears now have a bigger knockback effect, which pushes enemies backwards, * astrology, astronomy, item room, treasure room, item room pool, h, blue, glow, Tears Down by exactly half (Tear delay * 2), The tears down from this item is a x2.0 multiplier after the formula, meaning it will always halve your tear rate (Unless you have Monstro's Lung or Soy Milk), UNLOCK: Unlock this item by beating Boss Rush with Eve, * item room, treasure room, item room pool, makeup, make up, black, grey, gray, square, eves mascara, When you die with this item, you respawn in the previous room as Dark Judas with 2 black hearts for health, Dark Judas has a damage multiplier of 2.00 (double Isaac's damage) and an additional +0.1 Speed, Dark Judas is considered a separate character by the game, however he can be used to unlock Judas' secrets/achievements, REPENTANCE - Dark Judas can no longer gain red heart containers, HP upgrades give soul hearts instead, UNLOCK: Unlock this item by beating Boss Rush with Judas, * devil pool, devil room pool, devil deal, item room, treasure room, item room pool judas shadow, All future red hearts now heal for double. This will heal red hearts and then give soul hearts up to a total of 6. with Lilith, After picking up 15 hearts, Isaac gains a permanent angelic familiar and a soul heart drops, Possible familiars include: Holy Water, Guardian Angel, Sworn Protector, The Relic and Seraphim, It is possible to get multiple followers by continuing to pick up hearts, at intervals of 15 hearts each, After all 5 familiars have spawned, it will just drop a soul heart every 15 hearts collected, UNLOCK: Unlock this item by beating Boss Rush with Lilith, Two items now spawn in each of your item rooms, however only one can be taken and the other will disappear, A crown that replaces normal tears with blue diamond tears while you don't have any empty red heart containers or bone hearts, While the effect is active, tears do double damage and have -0.30 Shot Speed, The crown will glow blue while active, if inactive it will appear grey, The effect will also deactivate for the rest of the current room when you take damage, regardless of your health, When a room clear would otherwise yield no rewards, it now spawns 1-3 pennies, REPENTANCE - Deep Pockets no longer adds a pill/card slot, instead increases money cap to 999, UNLOCK: Unlock this item by beating The Chest floor with Keeper, A flying familiar that bounces around the room with a damaging aura, dealing rapid damage to any enemies inside it and boosting Isaac's tear damage, While standing in the black aura, Isaac has a temporary 1.5x damage multiplier (this will stack if you have more than one Succubus), The aura deals 2.5 damage per tick or about 7.5 - 10 damage per second, UNLOCK: Unlock this item by beating The Lamb with Lilith, Gives you a different tear effect with every tear that you fire, Tear effects include: Anti-Gravity, Ball of Bandages (Lvl 4), Bumbo (Lvl 3), Continuum, Cupid's Arrow, Compound Fracture, Euthanasia, Explosivo, Eye of Greed, Fire Mind, Flat Stone, Flat Worm, God's Flesh, Godhead, Head of the Keeper, Holy Light, Hook Worm, Ipecac, Iron Bar, Jacob's Ladder, Knockout Drops, Lachryphagy, Little Horn, Lodestone, Mom's Contacts, Mom's Eyeshadow, Mom's Perfume, Mucormycosis, My Reflection, Mysterious Liquid, Ocular Rift, Ouija Board, Ouroboros Worm, The Parasite, Parasitoid, Polyphemus, Pop!, Proptosis, Pulse Worm, Ring Worm, Rotten Tomato, Rubber Cement, Serpent's Kiss, Sinus Infection, Spider Bite, Strange Attractor, Sulfuric Acid, Technology Zero, Tiny Planet, Trisagion and Wiggle Worm, With Dr. Fetus, this item will also cycle through random Bomb Modifiers (e.g. Bad Trip becomes Balls of Steel. The Binding of Isaac is a randomly generated action RPG shooter with heavy Rogue-like elements. The priority list of what will drop from champion enemies in order is as follows: Soul Hearts - When you have no red heart containers and less than 2 soul hearts, Red Hearts (Full hearts) - While at 0.5 red hearts, Red Hearts (Full hearts) - When you have at least half a red heart container empty, Trinkets - If you have no trinkets and there are no trinkets on the ground in the room, Soul Hearts - When you have less than 6 total heart containers of any kind, If none of the above conditions are true, champions will resume dropping their regular pickups, UNLOCK: Unlock this item by defeating Greedier mode with Maggy, Allows you to fire tears diagonally by holding down two of the fire buttons at once, If you are using a gamepad, this item allows you to fire in any direction, The first enemy you kill in each new room will now explode and poison all nearby enemies, causing them to take periodic damage until they also die and explode, If you have lots of enemies near each other this can cause a chain reaction, killing lots of enemies in one go, Gives Isaac a finger which floats infront of him and points in the same direction he is facing or firing. Can be used with Placebo to generate infinite batteries, Amnesia - Hides the floor map for the rest of the current floor (same as curse of the lost). (Does not roll your devil deal items), 5 Dot - Reroll and restart the current floor (Forget Me Now effect), 6 Dot - Reroll all of your items and all the pickups on the entire floor (Combined 1 + 3 + 4 rooms), The same order as the in-game collection page. You can set the keys to whatever you want. The charge direction now allows for a minor amount of control, * headless horseman, headless horsemen, red, grey, gray, A bag of bombs that will drop a bomb pickup every 2 rooms, UNLOCK: Unlock this item by beating Satan with Cain, * boss rush pool, boss rush room, secret room pool, item room, treasure room, item room pool, This is how you use the basics of the Binding of Isaac: Afterbirth item editorLink for editor:http://www.mediafire.com/file/sghly3kuvhbs16u/isaac-character-e. Subscribed. They do not block enemy shots, UNLOCK: Unlock this item by defeating The Beast as Tainted Lilith, Isaac builds rage each time you clear a new room. Frozen enemies never unfreeze and are considered dead by the game. pill if no other pills were used yet. Following the path takes you to an abandoned mineshaft, which leads you to a pedestal with the Knife Piece. Any subsequent hits give +0.4 Tears Up and will ignore the normal fire rate cap, Greatly decreases damage (x0.33 damage multiplier), Individual tears gain random worm effects (e.g. Mr. Peppino in The Binding of Isaac : r/thebindingofisaac Soy Milk) can lead to interesting synergies, * astrology, astronomy, item room, treasure room, item room pool, ohm, blue, glow, Isaac's tears turn bright green and always apply a poison effect to enemies which deals a total of double your tear damage, This is essentially a superior version of The Common Cold item, * astrology, astronomy, item room, treasure room, item room pool, m, tail, blue, glow, Tears do not travel through rocks with this item, *astrology, astronomy, item room, treasure room, item room pool, nys, notyoursagittarius, There's Options, Double item room, Boss Rush) the Moving Box will pick only one of the items at random, Added as part of the Afterbirth+ Booster Pack #2 and based on the Steam Workshop mod created by HurleyFarrill, UNLOCK: Unlock this item by using Pandora's Box in the Dark Room floor, Your tears will now be connected together by beams of electricity which deals damage to enemies they hit, The lasers from this item deal 30% of your current damage stat, REPENTANCE - Technology Zero's lasers now deal 30% of the player's damage stat per tick (from 100%), UNLOCK: Unlock this item by having 2 technology items at once, *, black, white, grey, gray, round, circle, eye, key, hole, coin, slot, laser, Taking damage will spawn an orbital that rotates around Isaac, dealing contact damage to enemies and blocking enemy projectiles, A maximum of 3 Leprocy orbitals can be active at one time, Using the orbital to deal damage to enemies can cause it to break, Added as part of the Afterbirth+ Booster Pack #2. This mechanic is very useful on Greed and Greedier modes, UNLOCK: Unlock this item by defeating Delirium in The Void floor with Keeper, *, orange, brown, yellow, gold, coin, cent, Upon use this item hurts Isaac without actually taking health away, allowing you to activate any items which trigger when taking damage without losing health, UNLOCK: Unlock this item by defeating Delirium on The Void floor with Eve, When used, this item permanently removes one of your red heart containers and gives you a flat +0.2 Damage Up, the Anemic effect (+1.5 Range Up + red creep trail) and a Cube of Meat, The Anemic effect will only last for the current room, but the Cube of Meat and Damage Up are both permanent, Only works for red hearts and has no effect when used if you only have soul/black hearts, Has no recharge time and can be used as often as you like, It is possible to generate multiple meatboys by stacking more than 4 Cubes of Meat, When used, this item gives you the effect of a random item for the rest of the room, Using this item multiple times in the same room will replace the previous item's effect with a new one, Certain items can be activated with this item which have unexpected effects and many items will do nothing, Items do not grant consumable drops which would normally occur when that item is picked up, Most flight-granting items have cosmetic effects only, and will not allow you to fly, Items that usually give HP up will not give extra health when gained from Metronome, UNLOCK: Unlock this item by defeating Greedier Mode with Eden, This dice allows you to press the Drop key to cycle between all possible dice effects and pick one to use, Charge time scales based on the chosen dice, updating every time you use it, Possible dice include: D1, D4, D6, D8, D10, D12, D20, D100. The chance for a Red Room to unlock increases as you pick up more Crystal Keys. ONLY ANGEL DEAL ITEMS! (Special Challenge) - The Binding Of Isaac Poison deals 5 damage initially and then 3.5, UNLOCK: Unlock this item by beating Blue Womb (Hush) with Isaac, REPENTANCE - GB Bug is now a thrown projectile, activated by double tapping an attack button. This means you need a way to teleport out of the Mom's Foot boss fight. smile, lil' brimstone, Prevents Isaac from taking any damage, but instead summons a familiar heart that follows you around. They can be used to damage enemies, Saturnus tears can't break objects such as poop and TNT barrels, Isaac now shoots ice tears that slow enemies. box, yellow, grey, When used, converts 1 soul/black heart into 1 red heart container, This item will take from your soul hearts first, REPENTANCE - Converter now only costs one soul heart to use (previously costed two), * shop room pool, shop item pool, the lost item pool, blue, gray, grey, yellow, sprocket, When used, this item will spawn a set of items or consumables based on which chapter you are currently on, Basement 1: 2 Soul hearts. Larry Jr.) it will split them into 2 smaller enemies with half the number of sections they used to have, If the enemy normally has a mechanic that splits it (e.g. Sort: Item ID Colour Alphabetical Isaac Cheat Sheet. It can be anything including spawning a bunch of consumables, spawning a glitched pedestal item, creating a bunch of light beams, spawning troll bombs or nothing at all, UNLOCK: Unlock this item by defeating The Beast as Eden, "Isaac and his mother lived alone in a small house on a hill", When picked up, all future items become 'glitched', causing them to become random combinations of 2-3 effects based on other items, Glitched items can be passive or active and are completely randomly generated with infinite possibilities (similar to other 'Randomizer' games), The ratio of active to passive item effects given is 1/4, Random effects combine effects that exist on other items, and assign them to a random event (e.g. After the sword falls, extra items will no longer spawn, UNLOCK: Unlock this item by defeating The Lamb as Jacob & Esau, Upon use, spawns a giant puddle of lemonade that deals 8 damage per tick to any enemies which come in contact with it, Your tears are replaced with a sword which can be swung to deal damage (Damage * 3 + Base Damage). By Jack This guide will give you the BASICS of all items. Using this card will also open a pathway of red rooms back to the regular floor, UNLOCK: Unlock this card by defeating Ultra Greedier mode as Tainted Jacob, "May the darkness swallow all around you", When used, grants +1.5 Damage Up, turns your hearts to Bone hearts and the Spirit of the Night effect (Spectral tears and the ability to fly) for the current floor, Also gives the Curse of Darkness effect that can't be removed for the current floor, UNLOCK: Unlock this card by defeating Ultra Greedier mode as Tainted Lazarus, Creates a trapdoor to a guaranteed crawl space, UNLOCK: Unlock this card by defeating Ultra Greedier mode as Tainted Eden, When used, this copies the effect of the card, pill, rune, soul stone or active item you used most recently, UNLOCK: Unlock this card by defeating Mega Satan as Tainted Eden, Turns all pedestal items in the current room into rotating items, which cycle between the old item and a random new item every second, This allows you to effectively reroll items like with The D6, but choose the old item as well if you want, Tainted Isaac has this effect passively for all items, If you use more than one in the same room, each pedestal item will cycle through +1 random item, Items are chosen from the item pool related to the current item, UNLOCK: Unlock this item by defeating Hush and Boss Rush as Tainted Isaac, When used, all enemies in the current room drop half a red heart that will disappear after 2 seconds if not picked up, UNLOCK: Unlock this item by defeating Hush and Boss Rush as Tainted Magdalene, When used, this Soul Stone creates Red rooms for every possible exit in the current room, Red outlines of doors appear where this Soul Stone will create exits for, See the Red Key item description for more information about these Red rooms behave, UNLOCK: Unlock this item by defeating Hush and Boss Rush as Tainted Cain, Activates the Dark Arts item effect, which turns Isaac into a ghost for a few seconds.